Antiretroviral (ARV) Drugs

No Comments » December 28th, 2006 posted by // Categories: HIV/AIDS-in-Africa Project


Antiretroviral (ARV)

Source :



Inhibitors    –  Pharmaceutical

(Fuzeon, T-20)  – Roche

Fusion inhibitors work
by blocking the HIV virus from entering human cells.



Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs) –
 Pharmaceutical Company 

(Rescriptor)  –  Pfizer

   Efavirenz (Sustiva) 
– Bristol-Myers-Squibb

   Nevirapine (Viramune) 
– Boehringer Ingelheim Pharmaceuticals Inc 

The class of
Antiretroviral drugs called non-nucleoside reverse transcriptase inhibitor (NNRTI)
blocks reverse transcriptase, an enzyme that HIV needs to make more copies of



Nucleoside Reverse
Transcriptase Inhibitors (NRTIs)

    Abacavir (Ziagen)   –

   Abacavir + Lamivudine (Epzicom) 
– GlaxoSmithKline

Abacavir+Lamivudine+Zidovudine (Trizivir)  –

   Didanosine (Videx, ddI) 
– Bristol – Myers Squibb Co

   Emtricitabine (Emtriva,
FTC)  – Gilead Sciences Inc

   Emtricitabine +
Tenofovir DF (Truvada)  – Gilead Sciences Inc

   Lamivudine (Epivir,
3TC)  – GlaxoSmithKline

   Lamivudine+Zidovudine (Combivir) 
– GlaxoSmithKline

   Stavudine (Zerit, d4T) 
– Bristol – Myers Squibb Co

   Tenofovir DF (Viread) 
– Gilead Sciences Inc

Zalcitabine (Hivid, ddC)  –
   Roche Laboratories

Zidovudine (Retrovir, AZT, ZDV)  –

The class of
 antiretroviral drug called nucleoside reverse transcriptase inhibitor (NRTI)
 blocks reverse transcriptase, an enzyme (protein that helps chemical reactions)
that HIV needs to make more copies of itself.



Inhibitors (PIs)  – Pharmaceutical Company 

   Amprenavir (Agenerase) 
– GlaxoSmithKline

   Atazanavir (Reyataz)  –
Bristol – Myers Squibb Co

   Fosamprenavir (Lexiva,
908)  –  GlaxoSmithKline

   Indinavir (Crixivan)  –
Merck & Company, Inc

   Lopinavir+Ritonavir (Kaletra) 
– Abbott Laboratories

   Nelfinavir (Viracept) 
 Agouron Pharmaceuticals Inc

   Ritonavir (Norvir)  –
Abbott Laboratories

   Saquinavir (Fortovase,
Invirase)  – Roche Laboratories

The class of
antiretroviral drugs called protease inhibitors (PIs) act by blocking protease,
a protein that HIV needs to make more copies of itself.


 Date: December 27, 2004

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